Office Location: Mudd 648
Area of Specialization: Biochemistry
I am a graduate student in Damien Thévenin’s lab. Previously published work focused on an immunotherapy using a fusion of a pH-sensitive peptide and a nanobody to target cancer cells in their acidic environment. The targeted cancer cells displayed the nanobody on their surface such that they were subsequently destroyed by natural killer cells, while sparing healthy cells at a neutral pH. Current work is aimed at expressing and purifying the transmembrane and intracellular domains of a class of membrane proteins and reconstituting them in nanodiscs as a lipid membrane mimic. Further experiments will be conducted in order to understand the structure and activity of the reconstituted proteins. In my free time, I enjoy music, playing the guitar, ukulele, and piano, crocheting, reading, and walking on nature trails.