I am a photochemist who uses ultrafast and nanosecond laser spectroscopy to measure photophysics and photochemistry that occur on the picosecond (ps) to microsecond (μs) times scales in a wide range of chemistry. For example, Nature uses photochemistry that occurs on this time scale to carry out numerous functions critical to plant and human existence. The light-harvesting complex of photosynthesis starts the process by which plants convert sunlight into chemical energy, phytochromes are responsible for a plant’s ability to grow towards light, and light-sensitive rhodopsin enables human vision. Each of these processes is activated by light that leads to ultrafast chemical reactions. Rhodopsin, as an example, mediates dim light vision. When rhodopsin is exposed to light, its retinal cofactor isomerizes from the cis to trans configuration, and the protein undergoes a series of relaxations to accommodate the altered shape of the isomerized cofactor that results in our ability to see. The initial isomerization (0.2 ps) is followed by a series of reaction intermediates that have been mapped out using time-resolved spectroscopy to uncover the mechanism of vision.
At the center of my research efforts is transient absorption spectroscopy (TAS). TAS allows me to instantaneously (0.1 ps) initiate a chemical event and monitor (with sub-ps resolution) the progress of a reaction to identify the fates of photogenerated species. Research in my laboratory has quantified photoinduced charge-transfer dynamics and developed models for charge carrier mechanisms operative in thin films of light-absorbing materials used in solar cells; identified and controlled photoisomerization reactions of azo dyes known to convert photonic energy to potential energy, and developed reactions to degrade azo dye pollution released from the textile industry; uncovered new photophysical pathways in designer porphyrinoid moieties that can be used for a wide range of applications including photodynamic therapy; and designed excited-state proton-coupled electron transfer reactions in which the movement of both electrons and protons can lead to new reaction mechanisms and more facile reaction kinetics.