"Synthesis and applications of main-group organometallics: C-H borylation in the synthesis of alkylboronate esters"
We have identified that dipyridylarylmethane ligand-supported iridium complexes are highly active catalysts for the C-H borylation of unactivated alkanes to give alkylboronate esters. Our studies show that a series of isolable iridium hydridoboryls serve as the resting state species during catalysis and function as excellent single-source precatalysts. We have applied the products of alkane C-H borylation as nucleophilic coupling partners in Pd-catalyzed cross-coupling methods.